Which over-the-counter medication was subject to the largest product recall in pharmaceutical history after the 1982 Chicago Tylenol murders, leading to the development of tamper-evident packaging?

Product recalls in medicine are crucial quality control measures that protect patient safety. While most recalls affect limited batches or specific regions, some have been so extensive they changed industry practices forever. This trivia question explores one of the most significant pharmaceutical product recalls in history, which not only impacted millions of consumers but also led to major regulatory reforms and packaging innovations in the medicine industry.

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Tylenol (acetaminophen)
Advil (ibuprofen)
Bayer (aspirin)
Aleve (naproxen sodium)