Which groundbreaking scientific product innovation was initially rejected by its target market because researchers believed it would fundamentally change established laboratory protocols too drastically?

In the rapidly evolving world of scientific product development, breakthrough innovations often face significant challenges before reaching market success. This trivia question explores a famous case of product innovation that revolutionized scientific research but faced initial skepticism. Test your knowledge about pivotal moments in science product history!

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Polymerase Chain Reaction (PCR) technology, which was considered too complex and unreliable when first introduced in 1983
Electron microscopy, which scientists initially rejected as producing images too abstract to be scientifically useful
CRISPR gene editing technology, which faced market resistance due to concerns about its excessive simplicity compared to existing methods
Nuclear Magnetic Resonance (NMR) spectroscopy, which was dismissed as too expensive with insufficient precision for research applications