Which major shift in pharmaceutical brand positioning occurred during the 1990s that fundamentally changed how prescription medications were marketed?

The positioning of pharmaceutical brands has evolved dramatically over the decades, reflecting changes in medical science, regulatory environments, and consumer attitudes. This trivia question explores a significant shift in how medical products have been marketed to both healthcare providers and patients, highlighting an important turning point in pharmaceutical brand strategy.

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Direct-to-consumer advertising became legal and widespread in the US
Pharmaceutical companies began positioning drugs primarily based on price rather than efficacy
Medical brands shifted entirely to digital-only marketing, abandoning print materials for physicians
Prescription medications began to be marketed exclusively through hospital formulary committees rather than to physicians