Which innovative pharmaceutical packaging technology was first widely adopted around 2018 and has been shown to improve medication adherence by over 30% in clinical studies?

The pharmaceutical and medical device industries have seen significant changes in packaging design over the past decade. Smart packaging with temperature indicators, anti-counterfeiting measures, and patient compliance features have revolutionized how medical products reach consumers. This trivia question focuses on recent innovations in medical product packaging that have improved patient safety and medication adherence.

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RFID-enabled smart blister packs that track when pills are removed and send reminders to patients
Color-changing packaging that indicates when a medication has been exposed to temperature extremes
Biodegradable plant-based packaging materials that dissolve after disposal
3D-printed customized pill organizers with personalized dosing instructions