Which revolutionary scientific product initially failed in the marketplace because it was marketed as 'artificial' when consumers wanted 'natural', before being successfully rebranded?

In the competitive world of scientific innovation, how companies market their breakthroughs can be just as important as the discoveries themselves. Sometimes, even groundbreaking products can fail due to marketing missteps. This trivia question explores a famous case where brilliant science met poor brand strategy, resulting in a cautionary tale for the industry.

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NutraSweet (aspartame sweetener)
Kevlar (synthetic fiber)
Teflon (non-stick coating)
Taxol (cancer treatment)