Which breakthrough technology was first approved by the FDA as a 'digital pill' that can track if patients have ingested their medication?

The pharmaceutical industry is constantly evolving with technological advancements. One area seeing remarkable innovation is 'smart pills' - ingestible sensors and medication delivery systems that are changing patient monitoring and treatment adherence. These intelligent medications represent the intersection of medicine, technology, and product innovation, creating new possibilities for healthcare providers and patients alike.

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Abilify MyCite (aripiprazole with embedded sensor)
PillCam COLON (camera capsule endoscopy)
Proteus Discover (standalone ingestible sensor system)
IntelliCap (electronic controlled release capsule)