Which medical product innovation was first to use mRNA technology that later became crucial during the COVID-19 pandemic?

The pharmaceutical and medical device industries constantly innovate to improve patient outcomes and treatment efficacy. Product innovation in medicine requires extensive research, clinical trials, and regulatory approval processes before reaching patients. This trivia question tests your knowledge about a groundbreaking medical product launch that transformed treatment paradigms and set new standards for product innovation in healthcare.

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Moderna's cancer vaccines (in clinical trials before COVID-19)
Johnson & Johnson's Ebola vaccine
Medtronic's artificial pancreas system
Gilead's HIV treatment Biktarvy