Which controversial scientific product launch led to the establishment of the first major pharmaceutical regulatory framework in the United States?

Scientific innovation often brings both excitement and ethical questions. Throughout history, some product launches in science and technology have sparked intense debate about responsibility, safety, and societal impact. This trivia question explores a notable case that changed how we think about product development ethics in scientific fields.

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The Elixir Sulfanilamide disaster of 1937, which caused over 100 deaths due to a toxic solvent
The Thalidomide crisis of the early 1960s, which caused thousands of birth defects
The Three Mile Island nuclear accident of 1979, which led to radiation exposure concerns
The DES (diethylstilbestrol) hormone treatment of the 1940s-50s, which later caused reproductive cancers