Which scientific instrument, first commercially sold in 1974, revolutionized laboratory work and created a multi-billion dollar retail category still growing today?

In the world of science retail, certain products have fundamentally changed how researchers and laboratories operate. One particular scientific instrument revolutionized multiple fields and created an entirely new retail category worth billions. This instrument went from specialized laboratory equipment to becoming essential in numerous scientific applications, creating one of the most successful product category expansions in scientific retail history.

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High-Performance Liquid Chromatography (HPLC) Systems
Scanning Electron Microscopes (SEM)
PCR Thermal Cyclers
Mass Spectrometers