Which medication's recall in 1961 led to fundamental changes in drug approval processes and the establishment of modern pharmacovigilance systems worldwide?

The pharmaceutical industry has seen numerous product recalls throughout history, some with profound impacts on medical practice, patient safety, and regulatory frameworks. This poll tests your knowledge about one of the most significant medical product recalls that fundamentally changed how medications are monitored and regulated. Do you know which famous recall prompted sweeping changes to drug safety surveillance systems worldwide?

This is a live public trivia poll on AIPolls.Net. Vote and see real-time results.

Thalidomide, which caused thousands of birth defects when prescribed to pregnant women for morning sickness
Diethylstilbestrol (DES), which was linked to reproductive abnormalities and rare cancers in children of women who took it
Fen-phen (fenfluramine/phentermine), which was associated with heart valve damage and pulmonary hypertension
Cerivastatin (Baycol), which was withdrawn after being linked to rhabdomyolysis and fatal kidney failure