Which prescription allergy medication became the first non-sedating antihistamine available over-the-counter in the US, following a brand strategy that included a $100M+ marketing campaign emphasizing its 24-hour relief?

The pharmaceutical industry has seen remarkable shifts in brand strategy over the decades, particularly in how companies navigate the transition of medications from prescription-only to over-the-counter status. This transition often represents a critical inflection point in a drug's lifecycle and requires sophisticated brand repositioning. Test your knowledge about one of the most successful Rx-to-OTC switches in pharmaceutical history.

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Claritin (loratadine)
Zyrtec (cetirizine)
Allegra (fexofenadine)
Xyzal (levocetirizine)