Which pharmaceutical product was the first to achieve annual sales exceeding $1 billion, establishing the concept of a 'blockbuster drug' in the medical industry?

The pharmaceutical industry constantly evolves through innovation, market trends, and strategic partnerships. This poll explores a significant market trend that transformed both treatment approaches and corporate dynamics in the medical sector. Test your knowledge about how certain medications achieved unprecedented commercial success while revolutionizing patient care, and learn about the market forces that shaped modern medicine.

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Tagamet (cimetidine) - SmithKline (1979)
Prozac (fluoxetine) - Eli Lilly (1988)
Valium (diazepam) - Hoffmann-La Roche (1963)
Zantac (ranitidine) - Glaxo (1981)