Which packaging innovation revolutionized vaccine distribution in remote areas by eliminating the need for refrigeration in the 'cold chain'?

The science industry has seen remarkable innovations in product packaging that not only protect sensitive materials but also address environmental concerns. From temperature-controlled containers to biodegradable solutions, scientific product packaging has evolved dramatically. This trivia question explores a groundbreaking packaging innovation that changed how scientific products are distributed and used worldwide.

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Vacuum Thermal Insulation (VTI) containers
Freeze-dried vaccine formulations with temperature-stable adjuvants
Solar-powered portable refrigeration units
Phase-change material (PCM) cooling packs