Which pharmaceutical advertising innovation, first approved by the FDA in 1997, dramatically changed how medical companies market directly to patients?

In recent years, pharmaceutical and medical device companies have dramatically transformed their advertising strategies to reach healthcare professionals and patients. Digital platforms have revolutionized how medical products are marketed, creating new ethical considerations and regulatory challenges. This trivia question focuses on a significant shift in pharmaceutical advertising that changed the healthcare marketing landscape forever.

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Direct-to-consumer (DTC) prescription drug television advertisements
Sponsored medical influencers on social media platforms
QR codes on medication packaging linking to clinical trials
Virtual reality demonstrations of medical devices for patients