Which revolutionary pharmaceutical product innovation was the first to generate over $1 billion in annual sales (becoming the first 'blockbuster drug') and transformed both patient care and pharmaceutical retail distribution?

The pharmaceutical and medical device industries have revolutionized healthcare through groundbreaking product innovations. These innovations have transformed patient care, extended lifespans, and improved quality of life worldwide. This trivia question focuses on a notable product innovation milestone that changed the landscape of modern medicine and retail pharmacy distribution.

This is a live public trivia poll on AIPolls.Net. Vote and see real-time results.

Tagamet (cimetidine) - the first H2 blocker for ulcers (1976)
Valium (diazepam) - the breakthrough anti-anxiety medication (1963)
Inderal (propranolol) - the first beta-blocker for heart conditions (1964)
Feldene (piroxicam) - the once-daily NSAID pain reliever (1982)